THE EFFECT OF WHOLE SEED (Barringtonia racemosa) WATER EXTRACT ON ERYTHROCYTE, HEMOGLOBIN AND HEMATOCRITE COUNT OF WHITE RAT (Rattus norvegicus) EXPOSED TO CIGARETTE SMOKE

This study aims to determine the effect of Barringtonia racemosa seed extract on number erythrocytes, hemoglobin levels, and percentage hematocrit in white rats (Rattus norvegicus) exposed cigarette smoke. A total 25 Wistar strain, aged 3-4 months, male, weighing 180-200 g, were randomly divided into 5 treatment groups, each group consisting rats. Positive control (KP) without exposure smoke administration extract, negative (KN) extract. Treatment groups P1, P2, P3 given seeds with doses 50, 100, 150 mg/kg BW/day, respectively. The was administered orally for 30 days. Blood collection all carried out via orbital vein using a pipette after had been sedated 0.2 mL ketamine. Erythrocyte, hemoglobin, values calculated hematology analyzer. Data analyzed one-way pattern analysis variance (ANOVA). results showed that giving at 100 mg/kg/day significant (P0.05) increasing compared which not In conclusion, can increase